Inheritance of dermoid sinus in the Rhodesian ridgeback.

Autosomal dominant mutation causing the dorsal ridge predisposes for dermoid sinus in Rhodesian ridgeback dogs.

OBJECTIVES To define the mode of inheritance of the dorsal ridge and investigate if the ridge predisposes to the congenital abnormality dermoid sinus in the Rhodesian ridgeback. METHODS Segregation analysis was performed, including 87 litters (n=803) produced in Sweden between 1981 and 2002. Data were corrected to avoid bias in the segregation ratio. Chi-squared analysis was performed includi...

Dermoid sinus in a Rhodesian Ridgeback.

The origin of the Ridge and Associated Anomalies in Rhodesian Ridgebacks

Salmon Hilbertz, N.H.C. The origin of the ridge and associated anomalies in Rhodesian Ridgebacks. Doctor’s dissertation. ISSN: 1652-6880, ISBN: 978-91-85913-32-9 The thesis presents studies on the inheritance of the dorsal hair ridge and Dermoid Sinus (DS) in Rhodesian Ridgeback dogs. DS is classified as a neural tube defect in humans. Thus, the dog is proven to be an excellent comparative mode...

Multiple dermoid sinuses of type Vb and IIIb on the head of a Saint Bernard dog

Dermoid sinus, a congenital malformation of neural tube development, has been reported in humans and several animal species including dogs. It is typically found in the dorsal midline and commonly occurs in the Rhodesian Ridgeback breed. A case of multiple dermoid sinuses in the fronto-occipital region is described. An 11-month-old, intact female Saint Bernard dog was presented with a 2 day his...

Absence Seizures as a Feature of Juvenile Myoclonic Epilepsy in Rhodesian Ridgeback Dogs

Myoclonic epilepsy in Rhodesian Ridgeback (RR) dogs is characterized by myoclonic seizures occurring mainly during relaxation periods, a juvenile age of onset and generalized tonic-clonic seizures in one-third of patients. An 8-month-old female intact RR was presented for myoclonic seizures and staring episodes that both started at 10 weeks of age. Testing for the DIRAS1 variant indicated a hom...